You may have heard of Ellanse, a filler containing Policaprolactone (PCL), popularly known as Smart Filler. Smart Fillers are one of the most preferred anti-aging treatment methods recently. Smart Fillers, which are an injectable filler, have significant differences from hyaluronic acid content or fillers. While both are excellent treatments, the best choice will depend on your needs.

I’ll explain these differences as best I can about Ellansé so you can decide if it’s right for you.

What is Ellansé Smart Filler and How Does It Work?

Ellansé is a filler that does not contain hyaluronic acid. It is injected into the skin to gently lift, shape and restore the face while replacing the volume lost due to skin aging.  Its main component is Poly-Caprolactone (PCL) microspheres, a soft bioabsorbable medical polymer. PCL is suspended in a gel carrier made of carboxymethylcellulose (CMC).

When Ellansé is injected into the skin, it reverses skin aging in a 2-step process:

CMC gel gives instant lifting and shaping results. Collagen stimulation peaks at 12 weeks to deliver the final result.

At the same time, PCL microspheres begin to stimulate your skin to produce collagen. However, the effect of the gel only lasts for about 12 weeks.

Unlike hyaluronic acid fillers, which lift because of its gel properties, Ellanse works by stimulating your body to produce collagen. Results last 2 – 4 years.

Why Does Ellansé Smart Fillers Last Longer Than Other Dermal Fillers?  

Ellansé is made of microspheres that degrade differently from other fillers. When Ellansé enters your body, it goes through a process of “absorption” in which the molecules are gradually dissolved. The microspheres retain their original volume until nearly all the molecules have dissolved.

Longevity depends on the number of molecules that make up the spheres. The more molecules there are, the longer the result will take.

Which Areas Can Be Treated With Smart Fillers?

Ellansé is surprisingly versatile. Ellansé can be used to treat most areas that hyaluronic acid (HA) fillers can treat:

Temple Area


Nasolabial Folds

Lower Face, Marionette Lines


Jaw line



These areas are among the areas that can be treated with Smart Fillers.

Ellansé and Hyaluronic Acid Fillers 

I think both Ellansé and other Hyaluronic Acid (HA) fillers give excellent results.

Advantages of Ellansé over HA fillers:

Ellansé lasts longer than most HA fillers

Ellansé is more cost-effective in the long run

In rare cases, Ellansé does not cause the delayed hypersensitivity reactions (granuloma formation or hardened lump formation) that can occur with HA fillers.

Ellansé does not move because it works with your own collagen production. (HA fillers can be replaced in rare cases)

Ellansé retains its volume better over time.

Advantages of HA fillers over Ellansé include:

HA fillers have an antidote – when a problem arises they can be fixed. Thus, both minor (such as lumps) and major complications (eg, necrosis) can be treated more easily.

HA fillers give the skin a more moisture appearance. Therefore, they are also used as Skinboosters to improve skin texture.

HA fillers are better for fine-tuning in very sensitive areas like the undereye area.

HA fillers are cheaper.

If you suddenly decide to have surgery (for example, before nose surgery), HA fillers can dissolve. Ellansé cannot be dissolved and you will have to wait until it is absorbed in a few years.

What are the Possible Side Effects of Ellansé Smart Fillers?

Ellansé is very safe and most of the side effects are injection related – mild swelling, bruising and pain. These are temporary and will resolve with no issues.

The serious side effects of Ellansé are similar to those of other injectable fillers – necrosis (death of the skin) and blindness. These are extremely rare and can be minimized with good doctor technique.

Because Ellansé is insoluble, any excess filling cannot be easily removed – so it’s even more important to find a doctor you trust with enough experience to have the procedure done for you.

How Do I Know If I’m Eligible for Ellansé Smart Filler?

As you can see, Smart Fillers differ from other fillers in many ways. Deciding on the best filler for you depends on several factors detailed above that you should discuss with your doctor in-depth.

Ellansé is also more expensive than other hyaluronic acid fillers, but in the long run, you will enjoy the cost savings due to its longevity.

The outcome of your treatment will depend on a variety of factors, including your doctor’s experience, aesthetic taste, skin type, level of treatment compliance and, of course, your budget. 

After all these are evaluated, your doctor can recommend the most suitable filler for you and you can achieve the best results. 

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